Modification of hydroxyapatite/gelatin nanocomposite using polyacrylamide

Myung Chul Chang; Uk Kyu Kim; William H. Douglas

doi:10.1163/156856209X412218

Modification of hydroxyapatite/gelatin nanocomposite using polyacrylamide

Myung Chul Chang, Uk Kyu Kim, William H. Douglas

Restorative Sciences

Research output: Contribution to journal › Article › peer-review

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Abstract

A hydroxyapatite (HAp)/gelatin (GEL) nanocomposite was mixed with mineralized polyacrylamide (PAM) to produce a macrocomposite. The mineralization of PAM was carried out by solution-precipitation using Ca(OH)₂ and H₃PO₄. The crystal growth of HAp in PAM was moderately changed from amorphous-like nanocrystalline to crystalline with the increase of PAM. The dry body of HAp/PAM nanocomposite cracked after the immersion test in water, but the cross-linked sample using glutaraldehyde did not crack. The macrocomposite of HAp/GEL nanocomposite and HAp/PAM nanocomposite showed good toughness, but cracked after the immersion test in water. The cross-linked macrocomposite sample did not crack after the immersion test in water.

Original language	English (US)
Pages (from-to)	363-375
Number of pages	13
Journal	Journal of Biomaterials Science, Polymer Edition
Volume	20
Issue number	3
DOIs	https://doi.org/10.1163/156856209X412218
State	Published - Mar 1 2009

Keywords

Gelatin
Glutaraldehyde
Hydroxyapatite
Macrocomposite
Mineralization template
Polyacrylamide

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10.1163/156856209X412218

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title = "Modification of hydroxyapatite/gelatin nanocomposite using polyacrylamide",

abstract = "A hydroxyapatite (HAp)/gelatin (GEL) nanocomposite was mixed with mineralized polyacrylamide (PAM) to produce a macrocomposite. The mineralization of PAM was carried out by solution-precipitation using Ca(OH)2 and H3PO4. The crystal growth of HAp in PAM was moderately changed from amorphous-like nanocrystalline to crystalline with the increase of PAM. The dry body of HAp/PAM nanocomposite cracked after the immersion test in water, but the cross-linked sample using glutaraldehyde did not crack. The macrocomposite of HAp/GEL nanocomposite and HAp/PAM nanocomposite showed good toughness, but cracked after the immersion test in water. The cross-linked macrocomposite sample did not crack after the immersion test in water.",

keywords = "Gelatin, Glutaraldehyde, Hydroxyapatite, Macrocomposite, Mineralization template, Polyacrylamide",

author = "Chang, {Myung Chul} and Kim, {Uk Kyu} and Douglas, {William H.}",

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T1 - Modification of hydroxyapatite/gelatin nanocomposite using polyacrylamide

AU - Chang, Myung Chul

AU - Kim, Uk Kyu

AU - Douglas, William H.

PY - 2009/3/1

Y1 - 2009/3/1

N2 - A hydroxyapatite (HAp)/gelatin (GEL) nanocomposite was mixed with mineralized polyacrylamide (PAM) to produce a macrocomposite. The mineralization of PAM was carried out by solution-precipitation using Ca(OH)2 and H3PO4. The crystal growth of HAp in PAM was moderately changed from amorphous-like nanocrystalline to crystalline with the increase of PAM. The dry body of HAp/PAM nanocomposite cracked after the immersion test in water, but the cross-linked sample using glutaraldehyde did not crack. The macrocomposite of HAp/GEL nanocomposite and HAp/PAM nanocomposite showed good toughness, but cracked after the immersion test in water. The cross-linked macrocomposite sample did not crack after the immersion test in water.

AB - A hydroxyapatite (HAp)/gelatin (GEL) nanocomposite was mixed with mineralized polyacrylamide (PAM) to produce a macrocomposite. The mineralization of PAM was carried out by solution-precipitation using Ca(OH)2 and H3PO4. The crystal growth of HAp in PAM was moderately changed from amorphous-like nanocrystalline to crystalline with the increase of PAM. The dry body of HAp/PAM nanocomposite cracked after the immersion test in water, but the cross-linked sample using glutaraldehyde did not crack. The macrocomposite of HAp/GEL nanocomposite and HAp/PAM nanocomposite showed good toughness, but cracked after the immersion test in water. The cross-linked macrocomposite sample did not crack after the immersion test in water.

KW - Gelatin

KW - Glutaraldehyde

KW - Hydroxyapatite

KW - Macrocomposite

KW - Mineralization template

KW - Polyacrylamide

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DO - 10.1163/156856209X412218

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JO - Journal of Biomaterials Science, Polymer Edition

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IS - 3

ER -

Modification of hydroxyapatite/gelatin nanocomposite using polyacrylamide

Abstract

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