Modeling the repetitive firing of retinal ganglion cells

J. F. Fohlmeister, P. A. Coleman, Robert F Miller

Research output: Contribution to journalArticle

65 Scopus citations

Abstract

A kinetic model for the repetitive firing of retinal ganglion cells were synthesized from voltage-clamp data and evaluated by comparison with whole cell recordings from ganglion cells in the intact tiger salamander retina. Five distinct channels were included in the model and were sufficient to describe the physiologically observed frequency/current relationship in response to various levels of cell depolarization.

Original languageEnglish (US)
Pages (from-to)343-345
Number of pages3
JournalBrain Research
Volume510
Issue number2
DOIs
StatePublished - Mar 5 1990

Keywords

  • Channel kinetics
  • Computer modelling
  • Ganglion cell
  • Ion channel
  • Repetitive firing
  • Retina

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