Modeling and Synthesis of Human Growth Hormone Secretion Mechanism Using CAD tools

Nazeih Botros, Adil Akaaboune, Jaafar Alghazo

Research output: Contribution to conferencePaperpeer-review

5 Scopus citations

Abstract

In this paper we present a hardware realization of a simplified Human Growth Hormone (HGH) secretion mechanism. The mechanism is developed into a flowchart and then modeled using Hardware Descriptive Language (HDL). HDL behavioral modeling is implemented to simulate the behavior of the mechanism on the computer's screen. After verifying the simulation results, Computer Aided Design (CAD) tools are used to synthesize the mechanism onto Xilinx FPGAs chip. The chip is tested by inputting signals with values corresponding to the concentration of GHRH and the concentration of SRIF. A user-selected output pins on the chip show the concentration of HGH and the concentration of IGF-I. The outputs are compared with those generated by the simulation. Both the simulation and the chip generate identical patterns. We conclude that the chip mimics the HGH mechanism. The chip after synthesize is a stand-alone system that does not need a computer for operation. The chip operates on a real time basis.

Original languageEnglish (US)
Pages2429-2434
Number of pages6
DOIs
StatePublished - 2003
Externally publishedYes
EventThe 29th Annual Conference of the IEEE Industrial Electronics Society - Roanoke, VA, United States
Duration: Nov 2 2003Nov 6 2003

Other

OtherThe 29th Annual Conference of the IEEE Industrial Electronics Society
Country/TerritoryUnited States
CityRoanoke, VA
Period11/2/0311/6/03

Keywords

  • Field Programmable Gate Arrays (FPGAs)
  • Growth Hormone Releasing Hormone (GHRH)
  • Human Growth Hormone (HGH)
  • Insulinlike Growth Factor-I (IGF-I)
  • Somatostatin (SRIF)
  • Very High Speed Integrated Circuits Hardware Descriptive Language (VHDL)

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