Abstract
Mitotic spindles maintain a roughly constant length in metaphase, so the forces between the spindle poles are balanced. A new study involving screening molecules believed to mediate this force balance has found that spindle length is relatively insensitive to perturbations of molecular motor force-generating activities, but more sensitive to perturbation of microtubule assembly regulators and chromosome cohesion.
Original language | English (US) |
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Pages (from-to) | R956-R959 |
Journal | Current Biology |
Volume | 15 |
Issue number | 23 |
DOIs | |
State | Published - Dec 6 2005 |