Mitochondrial dysfunction in spontaneous inbred turkey cardiomyopathy

Jose Marin-Garcia, Radha Ananthakrishnan, Mary Ella Pierpont, Michael J. Goldenthal

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Mitochondrial enzyme activities were examined in cardiac tissues of turkeys with spontaneous inbred cardiomyopathy. Marked declines in specific enzyme activities were noted for respiratory complexes III and V ranging from 65-90% of the control values. No significant differences in complexes I, IV and citrate synthase nor in mitochondrial DNA copy number were detected. These results suggest that specific mitochondrial enzyme defects occur in cardiac tissues during spontaneous inbred turkey cardiomyopathy.

Original languageEnglish (US)
Pages (from-to)1087-1093
Number of pages7
JournalBiochemistry and Molecular Biology International
Volume38
Issue number6
StatePublished - Oct 17 1996

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