Mitochondrial apoptosis-inducing factor is involved in doxorubicin-induced toxicity on H9c2 cardiomyoblasts

Keyphrases

• Doxorubicin 100%
• Mitochondrial Apoptosis 100%
• Apoptosis-inducing Factor 100%
• H9c2 Cardiomyocytes 100%
• Induced Toxicity 100%
• Doxorubicin Toxicity 66%
• Cell Death 33%
• Caspase Inhibitor 33%
• H9c2 Cells 33%
• Doxorubicin Treatments 33%
• Western Blotting 16%
• Oxidative Stress 16%
• Small Interfering RNA (siRNA) 16%
• Apoptotic Cell Death 16%
• Mitochondria 16%
• Anticancer 16%
• Cardiotoxicity 16%
• Antioxidant 16%
• Limited Ability 16%
• Protease 16%
• Knockdown 16%
• Confocal Microscopy 16%
• Cardiac Cells 16%
• Treatment Results 16%
• DNA Fragments 16%
• Cell Death Pathways 16%
• Z-VAD-FMK 16%
• Pan-caspase Inhibitor 16%
• Calcium Homeostasis 16%
• Cathepsin B 16%
• Poly(ADP-ribose) Polymerase 16%
• P53 Activation 16%
• Cell Fraction 16%
• Cardiomyocyte Death 16%
• Calcium Activation 16%
• Nuclear Effects 16%
• Calpain Activity 16%

Biochemistry, Genetics and Molecular Biology

• Doxorubicin 100%
• Apoptosis-Inducing Factor 100%
• Caspase 40%
• Cell Death 30%
• Confocal Microscopy 10%
• Protease 10%
• Small Interfering RNA 10%
• Oxidative Stress 10%
• Mitochondrion 10%
• Calcium Homeostasis 10%
• Cardiac Muscle Cell 10%
• Western Blot 10%
• P53 10%
• Poly ADP Ribose Polymerase 10%
• Calpain 10%
• Cathepsin B 10%

Pharmacology, Toxicology and Pharmaceutical Science

• Doxorubicin 100%
• Apoptosis Inducing Factor 100%
• Caspase Inhibitor 30%
• Cardiotoxicity 10%
• Confocal Microscopy 10%
• Western Blot 10%
• Nicotinamide Adenine Dinucleotide Adenosine Diphosphate Ribosyltransferase 10%
• Malignant Neoplasm 10%
• Small Interfering RNA 10%
• Proteinase 10%
• Protein P53 10%
• DNA Fragment 10%
• Antioxidant 10%
• Caspase 10%
• Cathepsin B 10%
• Calpain 10%