Minimal Nucleation State of α-Synuclein Is Stabilized by Dynamic Threonine-Water Networks

Keyphrases

• Threonine 100%
• Alpha-synuclein (α-syn) 100%
• Protofibrils 100%
• Water Network 100%
• X-ray 50%
• Amino Acids 50%
• Molecular Dynamics Simulation 50%
• Dynamic Behavior 50%
• A53T 50%
• Water Molecule 50%
• Crystal Water 50%
• Simulation Strategy 50%
• Bulk Solvent 50%
• Greek Key 50%
• Nucleation Size 50%
• Water Coordination 50%
• Steric Zipper 50%

Biochemistry, Genetics and Molecular Biology

• Threonine 100%
• Nucleation 100%
• Synuclein 100%
• X Ray 33%
• Dynamics 33%
• Amino Acids 33%
• Crystal Structure 33%
• Volume 33%