Minimal important difference in Voice Handicap Index-10

Stephanie Misono, Bevan Yueh, Ali N. Stockness, Meaghan E. House, Schelomo Marmor

Research output: Contribution to journalArticlepeer-review

44 Scopus citations


IMPORTANCE: The minimal important difference (MID) on patient-reported outcome measures can indicate how much of a change on that scale is meaningful. OBJECTIVE: To use an anchor-based approach to estimate MID in the Voice Handicap Index-10 (VHI-10) total score. DESIGN, SETTING, AND PARTICIPANTS: In this cohort study, a volunteer sample of adult patients visiting the voice clinic at the University of Minnesota from April 7, 2013, through July 3, 2016, completed the VHI-10 (range, 0-40, with higher scores indicating greater voice-related handicap) at baseline and 2 weeks later in conjunction with a global rating of change. An anchor-based approach was used to identify an MID. The association between the global change score and change in VHI-10 score was analyzed using Pearson rank correlation. A distribution-based method was used to corroborate the findings. MAIN OUTCOME AND MEASURES: Global rating of change on the VHI-10.

Original languageEnglish (US)
Pages (from-to)1098-1103
Number of pages6
JournalJAMA Otolaryngology - Head and Neck Surgery
Issue number11
StatePublished - Nov 2017

Bibliographical note

Funding Information:
Funding/Support: This study was supported by grants KL2TR000113 and UL1TR000114 from the National Institutes of Health (Dr Misono).

Publisher Copyright:
© 2017 American Medical Association. All rights reserved.


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