Minichromosomes: Vectors for crop improvement

Jon P. Cody, Nathan C. Swyers, Morgan E. McCaw, Nathaniel D. Graham, Changzeng Zhao, James A. Birchler

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


Minichromosome technology has the potential to offer a number of possibilities for expanding current biofortification strategies. While conventional genome manipulations rely on random integration of one or a few genes, engineered minichromosomes would enable researchers to concatenate several gene aggregates into a single independent chromosome. These engineered minichromosomes can be rapidly transferred as a unit to other lines through the utilization of doubled haploid breeding. If used in conjunction with other biofortification methods, it may be possible to significantly increase the nutritional value of crops.

Original languageEnglish (US)
Pages (from-to)309-321
Number of pages13
Issue number3
StatePublished - Sep 1 2015

Bibliographical note

Funding Information:
Research on this topic was funded by National Science Foundation grant IOS-1339198.

Publisher Copyright:
© 2015 by the authors.


  • B chromosomes
  • Biofortification
  • Genetic engineering
  • Haploid induction
  • Minichromosomes
  • Telomere truncation


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