TY - JOUR
T1 - Millet-porridge with artemisia annua as first aid for African children with malaria?
AU - Bonati, Maurizio
AU - Severino, Francesca
AU - Bagnati, Renzo
AU - Carrà, Andrea
AU - Fanelli, Roberto
PY - 2011/4/1
Y1 - 2011/4/1
N2 - Objectives: In a few malaria-endemic countries with high disease prevalence, especially in children, and local cultivation of Artemisia annua, the availability of recommended malaria medicines is scant. New sources of treatment could be used, drawing from traditional medicine. Methods: A popular African millet-porridge was prepared by adding dried, sieved leaves of Artemisia annua. Artemisinin concentrations were detected by high-performance liquid chromatography-mass spectrometry. Results: The artemisinin content of the porridge is stable and the concentration is maintained. The taste of the porridge is palatable. Conclusions: Further research is needed before proposing the millet-porridge artemisinin formulation, but such an affordable therapy could be an option in the near future (also) for children living in poor areas where access to effective antimalarial drugs is precluded.
AB - Objectives: In a few malaria-endemic countries with high disease prevalence, especially in children, and local cultivation of Artemisia annua, the availability of recommended malaria medicines is scant. New sources of treatment could be used, drawing from traditional medicine. Methods: A popular African millet-porridge was prepared by adding dried, sieved leaves of Artemisia annua. Artemisinin concentrations were detected by high-performance liquid chromatography-mass spectrometry. Results: The artemisinin content of the porridge is stable and the concentration is maintained. The taste of the porridge is palatable. Conclusions: Further research is needed before proposing the millet-porridge artemisinin formulation, but such an affordable therapy could be an option in the near future (also) for children living in poor areas where access to effective antimalarial drugs is precluded.
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U2 - 10.1089/acm.2010.0252
DO - 10.1089/acm.2010.0252
M3 - Article
C2 - 21443445
AN - SCOPUS:79955038555
VL - 17
SP - 371
EP - 373
JO - Journal of Alternative and Complementary Medicine
JF - Journal of Alternative and Complementary Medicine
SN - 1075-5535
IS - 4
ER -