Mild-to-moderate symptoms during the first year of antiretroviral therapy worsen quality of life in HIV-infected individuals

Sharon B. Mannheimer, Nicholas Wold, Edward M. Gardner, Edward E. Telzak, Katherine Huppler Hullsiek, Margaret Chesney, Albert W. Wu, Rodger D. MacArthur, John Matts, Gerald Friedland

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

Symptoms and quality of life were assessed among human immunodeficiency virus (HIV)-infected individuals initiating their first course of antiretroviral therapy. Symptoms, which were mostly mild or moderate, were common in the first year and significantly affected the patients' quality of life. Quality of life was inversely related to the number of symptoms and in the change in the number of symptoms from baseline.

Original languageEnglish (US)
Pages (from-to)941-945
Number of pages5
JournalClinical Infectious Diseases
Volume46
Issue number6
DOIs
StatePublished - Mar 15 2008

Bibliographical note

Funding Information:
Financial support. The National Institute of Allergy and Infectious Diseases, National Institutes of Health (5U01AI042170-10 and 5U01AI046362-03) provided financial support for this work by the Community Programs for Clinical Research on AIDS Adherence Working Group as part of the FIRST study (CPCRA 058). Potential conflicts of interest. All authors: no conflicts.

Fingerprint Dive into the research topics of 'Mild-to-moderate symptoms during the first year of antiretroviral therapy worsen quality of life in HIV-infected individuals'. Together they form a unique fingerprint.

Cite this