Abstract
Regulation of mitochondrial calcium uptake by the mitochondrial calcium uniporter (mtCU) complex is crucial for heart function. In a recent study, Hasan et al. demonstrated that mitochondrial calcium uptake (MICU)1 and MICU2, regulatory subunits of the complex, help maintain calcium homeostasis in cardiac mitochondria, providing potential targets for therapies aimed at improving mitochondrial function in heart disease.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 950-952 |
| Number of pages | 3 |
| Journal | Trends in Pharmacological Sciences |
| Volume | 45 |
| Issue number | 11 |
| DOIs | |
| State | Published - Nov 2024 |
Bibliographical note
Publisher Copyright:© 2024 Elsevier Ltd
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- EMRE
- MCU
- MICU1
- MICU2
- calcium
- heart
- mitochondria
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