Microwave-assisted solid-phase peptide synthesis utilizing N-Fmoc-protected (α-aminoacyl)benzotriazoles

Alan R. Katritzky, Niveen M. Khashab, Megumi Yoshioka, Danniebelle N. Haase, Krista R. Wilson, Jodie V. Johnson, Alfred Chung, Carrie Haskell-Luevano

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


A novel microwave-assisted solid-phase peptide synthesis utilizing N-Fmoc-protected(α-aminoacyl)benzotriazoles was applied in the preparation of tri-, tetra-, penta-, hexa-, and heptapeptides in 71% average crude yield.

Original languageEnglish (US)
Pages (from-to)465-468
Number of pages4
JournalChemical Biology and Drug Design
Issue number5
StatePublished - Nov 2007


  • Microwave irradiation
  • N-Fmoc-protected(α-aminoacyl)benzotriazole
  • Peptides
  • Rink amide resin
  • Solid-phase peptide synthesis


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