Abstract
Natural Killer (NK) cell-based immunotherapies are becoming increasingly popular for treating solid tumors due to their role in tumor surveillance. However, much is still unknown about NK/cancer cell interactions in metastasis, including which stage of metastasis NK cells most often target cancer cells. Additionally, fundamental differences between murine and human immune systems limit the value of murine model systems in studying NK cell-based immunotherapies, such as Trispecific Killer Engagers (TriKEs). Therefore, we developed microfluidic models of metastasis to study NK/cancer cells interactions and TriKEs as an immunotherapy.
| Original language | English (US) |
|---|---|
| Title of host publication | MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 1153-1154 |
| Number of pages | 2 |
| ISBN (Electronic) | 9781733419017 |
| State | Published - 2020 |
| Event | 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020 - Virtual, Online Duration: Oct 4 2020 → Oct 9 2020 |
Publication series
| Name | MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
|---|
Conference
| Conference | 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020 |
|---|---|
| City | Virtual, Online |
| Period | 10/4/20 → 10/9/20 |
Bibliographical note
Publisher Copyright:© 2020 CBMS-0001
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Immunotherapy
- Metastasis
- Microfluidics
- Natural Killer Cells
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