Microfluidic generation of multifunctional quantum dot barcode particles

Yuanjin Zhao, Ho Cheung Shum, Haosheng Chen, Laura L.A. Adams, Zhongze Gu, David A. Weitz

Research output: Contribution to journalArticlepeer-review

211 Scopus citations

Abstract

We develop a new strategy to prepare quantum dot (QD) barcode particles by polymerizing double-emulsion droplets prepared in capillary microfluidic devices. The resultant barcode particles are composed of stable QD-tagged core particles surrounded by hydrogel shells. These particles exhibit uniform spectral characteristics and excellent coding capability, as confirmed by photoluminescence analyses. By using double-emulsion droplets with two inner droplets of distinct phases as templates, we have also fabricated anisotropic magnetic barcode particles with two separate cores or with a Janus core. These particles enable optical encoding and magnetic separation, thus making them excellent functional barcode particles in biomedical applications.

Original languageEnglish (US)
Pages (from-to)8790-8793
Number of pages4
JournalJournal of the American Chemical Society
Volume133
Issue number23
DOIs
StatePublished - Jun 15 2011
Externally publishedYes

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