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Methylene Blue - A therapeutic dye for all seasons?

  • M. Wainwright
  • , K. B. Crossley

Research output: Contribution to journal › Review article › peer-review

Abstract

Since it was first synthesised in 1876, Methylene Blue (MB) has found uses in many different areas of clinical medicine, ranging from dementia to cancer chemotherapy. In addition, MB formed the basis of antimicrobial chemotherapy - particularly in the area of antimalarials - and eventually led to the discovery of the neuroleptic drug families. More recently, the photosensitising potential of MB and its congeners has been recognised, and these are being applied in various antimicrobial fields, especially that of blood disinfection. The range of activities of MB is due to the combination of its simple chemical structure and facility for oxidation-reduction reactions in situ.

Original languageEnglish (US)
Pages (from-to)431-443
Number of pages13
JournalJournal of Chemotherapy
Volume14
Issue number5
DOIs
StatePublished - Oct 2002
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Anticancer
  • Antimicrobial
  • Blood
  • DNA
  • Malaria
  • Methylene Blue
  • Neuroleptic

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