Keyphrases
Induced Apoptosis
100%
Methotrexate
100%
Altered Expression
100%
Methylenetetrahydrofolate Reductase (MTHFR)
100%
Overexpressing
18%
Gene-deficient Mice
18%
Folate
18%
Spleen
18%
DNA Synthesis
18%
Myelosuppression
18%
Apoptotic Index
18%
Caspase 3/7 Activity
18%
Polymorphism
9%
DNA Methylation (DNAm)
9%
Overexpression
9%
Apoptosis
9%
Homocysteine
9%
Methionine
9%
Antifolate
9%
Metabolic Enzymes
9%
Littermate
9%
Terminal Deoxynucleotidyl Transferase dUTP Nick End Labeling
9%
Chemosensitivity
9%
Deoxyribonucleotides
9%
Activity Assay
9%
Homocysteine Levels
9%
End-labelling
9%
Hyperhomocysteinemia
9%
Deoxyribonucleoside Triphosphates
9%
Nucleotide Synthesis
9%
Therapeutic Implications
9%
Synthesis Reaction
9%
Methylenetetrahydrofolate Reductase Polymorphism
9%
Remethylation
9%
Methylation Reaction
9%
Methylenetetrahydrofolate Reductase Deficiency
9%
Transferases
9%
Underexpression
9%
Biochemistry, Genetics and Molecular Biology
Methylenetetrahydrofolate Reductase
100%
Methotrexate
100%
Programmed Cell Death
100%
DNA Synthesis
15%
Caspase 3
15%
TUNEL Assay
15%
Deoxyuridine
15%
Homocysteine
15%
Genotyping
7%
Wild Type
7%
Terminal Deoxynucleotidyl Transferase
7%
Enzyme
7%
DNA Methylation
7%
Nucleotide Metabolism
7%
Chemosensitivity
7%
Transferase
7%
Folic Acid
7%
Antifolate
7%
Thymidine Triphosphate
7%
Blood Plasma
7%
Methionine
7%
Deoxyribonucleotide
7%
Deficiency
7%
Neuroscience
Methotrexate
100%
5,10 Methylenetetrahydrofolate Reductase (FADH2)
100%
Programmed Cell Death
100%
Caspase 3
15%
Deoxyuridine
15%
DNA Synthesis
15%
Homocysteine
15%
TUNEL Assay
15%
DNA Methylation
7%
Staining Technique
7%
Transferase
7%
Folic Acid
7%
Thymidine Triphosphate
7%
Deoxyribonucleotide
7%
Methionine
7%
Folate
7%
DNA Nucleotidylexotransferase
7%
Antifolate
7%
Blood Plasma
7%
Pharmacology, Toxicology and Pharmaceutical Science
Methotrexate
100%
5,10 Methylenetetrahydrofolate Reductase (FADH2)
100%
Folic Acid
15%
Homocysteine
15%
Caspase 3
15%
Bone Marrow Suppression
15%
Deoxyuridine
15%
Folic Acid Antagonist
7%
Antiinfective Agent
7%
Methionine
7%
DNA Nucleotidylexotransferase
7%
Hyperhomocysteinemia
7%
Transferase
7%
Deoxyribonucleotide
7%
Thymidine Triphosphate
7%
Immunology and Microbiology
Methotrexate
100%
Programmed Cell Death
100%
DNA Synthesis
20%
Caspase
20%
Homocysteine
20%
Blood Plasma
10%
Nucleotide Metabolism
10%
Chemosensitivity
10%
DNA Methylation
10%
Wild Type
10%
Methionine
10%