Keyphrases
Transgenic
100%
Multidrug-resistant
100%
Marrow
100%
Methotrexate
100%
Methylenetetrahydrofolate Reductase (MTHFR)
35%
Gastrointestinal Tissues
21%
Hematopoietic Tissue
14%
Methotrexate Toxicity
14%
Gene Expression
7%
Transgenic Mice
7%
Pharmacokinetic Study
7%
Gene Transfer
7%
Transplantation
7%
High Dose
7%
Hematopoietic Cells
7%
Antitumor Efficacy
7%
Drug Toxicity
7%
Antifolate
7%
Drug Sensitivity
7%
Intestine
7%
Between-group
7%
Hematocrit Level
7%
Marrow Transplantation
7%
Comparisons with a Control
7%
Marrow Cells
7%
Hematopoietic System
7%
Plasma Tissue
7%
Reductase Activity
7%
Gastrointestinal Toxicity
7%
Resistant Variants
7%
Methotrexate Clearance
7%
4-fold
7%
Increased Dose
7%
Animal Resistance
7%
Pharmacology, Toxicology and Pharmaceutical Science
Methotrexate
100%
Dihydrofolate Reductase
29%
Transgenic Mouse
5%
Folic Acid Antagonist
5%
Drug Toxicity
5%
Gastrointestinal Toxicity
5%
Arginine
5%
Gene Delivery
5%
Pharmacokinetics
5%