TY - JOUR
T1 - Metastatic pattern in dogs with splenic haemangiosarcoma
T2 - Clinical implications
AU - WATERS, D. J.
AU - CAYWOOD, D. D.
AU - HAYDEN, D. W.
AU - Klausner, Jeffrey S
PY - 1988/12
Y1 - 1988/12
N2 - A retrospective study was undertaken to characterise the biological behaviour of splenic haemangiosarcoma (HSA) in dogs. Metastatic pattern data for 25 dogs with splenic HSA that were presented for clinical signs relating to splenic lesions (eg, abdominal mass and, or, haemoperitoneum) and had undergone necropsy were analysed. Six of 25 dogs with splenic HSA that were presented for abdominal mass/haemoperitoneum had right atrial HSA. Fifteen of 19 (79 per cent dogs) with splenic HSA associated with abdominal mass/hemoperitoneum without right atrial involvement had disease confined to the peritoneal cavity. The most common metastatic sites in these dogs were liver, omentum and mesentery. Extraperitoneal metastases were seen in four of 19 (21 per cent) dogs without right atrial involvement. Analysis of signalment data of dogs in this series and the literature revealed no differences between dogs with disease confined to the peritoneal cavity and dogs with extraperitoneal metastases. The subjectivity of primary site designation, importance of ante mortem identification of individuals with concurrent right atrial involvement, and need for more aggressive therapy directed at intraperitoneal metastases are discussed.
AB - A retrospective study was undertaken to characterise the biological behaviour of splenic haemangiosarcoma (HSA) in dogs. Metastatic pattern data for 25 dogs with splenic HSA that were presented for clinical signs relating to splenic lesions (eg, abdominal mass and, or, haemoperitoneum) and had undergone necropsy were analysed. Six of 25 dogs with splenic HSA that were presented for abdominal mass/haemoperitoneum had right atrial HSA. Fifteen of 19 (79 per cent dogs) with splenic HSA associated with abdominal mass/hemoperitoneum without right atrial involvement had disease confined to the peritoneal cavity. The most common metastatic sites in these dogs were liver, omentum and mesentery. Extraperitoneal metastases were seen in four of 19 (21 per cent) dogs without right atrial involvement. Analysis of signalment data of dogs in this series and the literature revealed no differences between dogs with disease confined to the peritoneal cavity and dogs with extraperitoneal metastases. The subjectivity of primary site designation, importance of ante mortem identification of individuals with concurrent right atrial involvement, and need for more aggressive therapy directed at intraperitoneal metastases are discussed.
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U2 - 10.1111/j.1748-5827.1988.tb01907.x
DO - 10.1111/j.1748-5827.1988.tb01907.x
M3 - Article
AN - SCOPUS:84985372978
SN - 0022-4510
VL - 29
SP - 805
EP - 814
JO - Journal of Small Animal Practice
JF - Journal of Small Animal Practice
IS - 12
ER -