Metal-based methods for protein inactivation

Jai Prakash; Jeremy J. Kodanko

doi:10.1016/j.cbpa.2012.12.011

Metal-based methods for protein inactivation

Jai Prakash
, Jeremy J. Kodanko

Chemistry (Twin Cities)

Research output: Contribution to journal › Review article › peer-review

15 Scopus citations

Abstract

Metal complexes are efficient catalysts for protein inactivation. Because of their special reactivity, metal-based molecules can achieve results that are difficult, if not impossible to obtain with more traditional, organic-based inhibitors. This article summarizes the chemistry of hydrolytic and oxidative catalysts for protein inactivation.

Original language	English (US)
Pages (from-to)	197-203
Number of pages	7
Journal	Current opinion in chemical biology
Volume	17
Issue number	2
DOIs	https://doi.org/10.1016/j.cbpa.2012.12.011
State	Published - Apr 2013

Bibliographical note

Funding Information:
We thank Wayne State University and the Thomas C. Rumble University Graduate Fellowship for support.

Publisher link

10.1016/j.cbpa.2012.12.011

Find It

Find It at U of M Libraries

Cite this

@article{26ca76bb78a5405993f12184594753db,

title = "Metal-based methods for protein inactivation",

abstract = "Metal complexes are efficient catalysts for protein inactivation. Because of their special reactivity, metal-based molecules can achieve results that are difficult, if not impossible to obtain with more traditional, organic-based inhibitors. This article summarizes the chemistry of hydrolytic and oxidative catalysts for protein inactivation.",

author = "Jai Prakash and Kodanko, \{Jeremy J.\}",

note = "Funding Information: We thank Wayne State University and the Thomas C. Rumble University Graduate Fellowship for support.",

year = "2013",

month = apr,

doi = "10.1016/j.cbpa.2012.12.011",

language = "English (US)",

volume = "17",

pages = "197--203",

journal = "Current opinion in chemical biology",

issn = "1367-5931",

publisher = "Elsevier Ltd",

number = "2",

}

TY - JOUR

T1 - Metal-based methods for protein inactivation

AU - Prakash, Jai

AU - Kodanko, Jeremy J.

N1 - Funding Information: We thank Wayne State University and the Thomas C. Rumble University Graduate Fellowship for support.

PY - 2013/4

Y1 - 2013/4

N2 - Metal complexes are efficient catalysts for protein inactivation. Because of their special reactivity, metal-based molecules can achieve results that are difficult, if not impossible to obtain with more traditional, organic-based inhibitors. This article summarizes the chemistry of hydrolytic and oxidative catalysts for protein inactivation.

AB - Metal complexes are efficient catalysts for protein inactivation. Because of their special reactivity, metal-based molecules can achieve results that are difficult, if not impossible to obtain with more traditional, organic-based inhibitors. This article summarizes the chemistry of hydrolytic and oxidative catalysts for protein inactivation.

UR - https://www.scopus.com/pages/publications/84876712773

UR - https://www.scopus.com/pages/publications/84876712773#tab=citedBy

U2 - 10.1016/j.cbpa.2012.12.011

DO - 10.1016/j.cbpa.2012.12.011

M3 - Review article

C2 - 23352647

AN - SCOPUS:84876712773

SN - 1367-5931

VL - 17

SP - 197

EP - 203

JO - Current opinion in chemical biology

JF - Current opinion in chemical biology

IS - 2

ER -

Metal-based methods for protein inactivation

Abstract

Bibliographical note

Publisher link

Find It

Other files and links

Fingerprint

Cite this