Metal-based methods for protein inactivation

Jai Prakash, Jeremy J. Kodanko

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations

Abstract

Metal complexes are efficient catalysts for protein inactivation. Because of their special reactivity, metal-based molecules can achieve results that are difficult, if not impossible to obtain with more traditional, organic-based inhibitors. This article summarizes the chemistry of hydrolytic and oxidative catalysts for protein inactivation.

Original languageEnglish (US)
Pages (from-to)197-203
Number of pages7
JournalCurrent opinion in chemical biology
Volume17
Issue number2
DOIs
StatePublished - Apr 2013

Bibliographical note

Funding Information:
We thank Wayne State University and the Thomas C. Rumble University Graduate Fellowship for support.

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