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Metabolism and DNA Binding of 5,6-Dimethylchrysene in Mouse Skin
Bijaya Misra
, Shantu Amin
,
Stephen S. Hecht
Laboratory Medicine and Pathology
Research output
:
Contribution to journal
›
Article
›
peer-review
17
Scopus citations
Overview
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Dive into the research topics of 'Metabolism and DNA Binding of 5,6-Dimethylchrysene in Mouse Skin'. Together they form a unique fingerprint.
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Keyphrases
Metabolism
100%
Mouse Skin
100%
DNA Binding
100%
1,2-Diols
100%
Epoxides
46%
Epidermis
23%
2′-Deoxyguanosine
23%
Metabolic Activation
15%
Liver
7%
Activation Mechanism
7%
Circulating Tumor DNA (ctDNA)
7%
Hydroxymethyl
7%
Supernatant
7%
Non-planar
7%
Deoxyribonucleosides
7%
Tumor Initiator
7%
Diol Epoxide
7%
Major Metabolites
7%
Tumorigenicity
7%
Topical Application
7%
4-diol
7%
Benzo
7%
Phenanthrene
7%
Deoxyadenosine
7%
Topical Treatment
7%
Total DNA
7%
HPLC Analysis
7%
Mouse Epidermis
7%
Aroclor 1254
7%
Enzymatic Hydrolysate
7%
4-fold
7%
Bay Area
7%
Low Activity
7%
Pharmacology, Toxicology and Pharmaceutical Science
Epoxide
100%
Deoxyguanosine
42%
High Performance Liquid Chromatography
14%
Phenanthrene
14%
Carcinogenicity
14%
Aroclor 1254
14%
Neoplasm
14%
Deoxyribonucleoside
14%
Deoxyadenosine
14%