Metabolic syndrome is independently associated with microalbuminuria in type 2 diabetes

Alireza Esteghamati, Armin Rashidi, Omid Khalilzedeh, Haleh Ashraf, Mehrshad Abbasi

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

We opted in this study to evaluate the association between metabolic syndrome (MetS) and microalbuminuria in type 2 diabetes. A total of 800 adults (344 males; age 54.8 ± 9.6 years) with type 2 diabetes were studied. MetS was defined by the International Diabetes Federation criteria and microalbuminuria by urinary albumin excretion between 30 and 299 mg/day on at least two of three occasions. Patients with macroalbuminuria and those with poor renal function were not included. Microalbuminuria was present in 237 (29.6%) patients withMetS and increased in prevalence with increasing numbers of metabolic abnormalities (P<0.001). The normo- and micro-albuminuric groups were not significantly different in age, sex, and renal function. However, MetS was significantly more common among patients with (90.3%) than those without (76.6%) microalbuminuria (P<0.01). Inmultivariate regression,MetSwas the strongest correlate of microalbuminuria (OR = 3.31, 95% CI = 1.91- 5.75; P<0.01). In conclusion, MetS is independently associated with microalbuminuria in type 2 diabetes.

Original languageEnglish (US)
Pages (from-to)125-130
Number of pages6
JournalActa Diabetologica
Volume47
Issue number2
DOIs
StatePublished - Jun 2010

Keywords

  • IDF
  • Metabolic syndrome
  • Microalbuminuria
  • Type 2 diabetes

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