Metabolic syndrome and periodontitis in Gullah African Americans with type 2 diabetes mellitus

Nicoleta D. Sora, Nicole M. Marlow, Dipankar Bandyopadhyay, Renata S. Leite, Elizabeth H. Slate, Jyotika K. Fernandes

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Aim To assess associations of metabolic syndrome, and its individual components, with extent of severe periodontitis among patients with type 2 diabetes mellitus (T2DM). Materials & Methods We performed a secondary data analysis (N = 283) using a cross-sectional study population of Gullah African Americans with T2DM. Extent of severe periodontitis was assessed as total diseased tooth-sites/person [evaluated as separate outcomes: 6+mm clinical attachment level (CAL), 5+mm periodontal probing depth (PPD)] using negative binomial regression techniques. Primary independent variables assessed in separate models included metabolic syndrome (yes/no), each metabolic syndrome component (low HDL, hypertension, high triglycerides, large waist circumference) and glycemic control (poor/good). Results Multivariable CAL-model results showed a significant association for metabolic syndrome status with extent of severe periodontitis (RR = 2.77, p = 0.03). The separate multivariable CAL-model including each metabolic syndrome component showed marginally increased rates among those with large waist circumference (RR = 2.33, p = 0.09) and those with HbA1c ≥ 7% (RR = 1.73, p = 0.06). Multivariable PPD-models showed marginally increased rates among those with metabolic syndrome (RR = 2.18, p = 0.06). Conclusion Metabolic syndrome is associated with the extent of severe periodontitis in this Gullah population with T2DM.

Original languageEnglish (US)
Pages (from-to)599-606
Number of pages8
JournalJournal of clinical periodontology
Volume40
Issue number6
DOIs
StatePublished - Jun 2013

Keywords

  • Gullah population
  • diabetes mellitus
  • metabolic syndrome
  • obesity
  • periodontitis

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