TY - JOUR
T1 - Metabolic effects of infection and postnatal steroids
AU - Schwarzenberg, Sarah Jane
AU - Kovacs, Andras
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2002
Y1 - 2002
N2 - Optimal development of the newborn depends on rapid accretion of substrate in the neonatal period, particularly in the premature infant. Steroids and infection not only induce catabolism, but associated endogenous responses reprioritize crucial substrate to restore homeostasis. The result is a protein/energy deficit and concomitant delay in growth and development. Innovative feeding strategies and novel therapies are needed to reduce the impact of catabolism in this population.
AB - Optimal development of the newborn depends on rapid accretion of substrate in the neonatal period, particularly in the premature infant. Steroids and infection not only induce catabolism, but associated endogenous responses reprioritize crucial substrate to restore homeostasis. The result is a protein/energy deficit and concomitant delay in growth and development. Innovative feeding strategies and novel therapies are needed to reduce the impact of catabolism in this population.
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U2 - 10.1016/S0095-5108(02)00003-9
DO - 10.1016/S0095-5108(02)00003-9
M3 - Review article
C2 - 12168243
AN - SCOPUS:0035990691
SN - 0095-5108
VL - 29
SP - 295
EP - 312
JO - Clinics in Perinatology
JF - Clinics in Perinatology
IS - 2
ER -