Meningiomas: Clinical needs and molecular insights

Saskia Peerdeman; Okay Saydam; Connie Jimenez

doi:10.1007/978-94-007-2894-3_5

Meningiomas: Clinical needs and molecular insights

Saskia Peerdeman, Okay Saydam, Connie Jimenez

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Meningiomas are common human brain tumors usually of benign nature. These brain tumors derive from arachnoidal cells associated with brain meninges. The etiology of incidental meningiomas is unknown. A predisposing factor is ionizing radiation. Some genetic syndromes like neurofibromatosis type 2 are associated with meningiomas. Here we highlight the clinical needs and review recent progress made in the field of genomics and proteomics. Finally, we focus on minichromosome maintenance proteins as potential novel markers for early diagnosis of meningioma.

Original language	English (US)
Title of host publication	Tumors of the Central Nervous System, Volume 7
Subtitle of host publication	Meningiomas and Schwannomas
Publisher	Springer Netherlands
Pages	39-46
Number of pages	8
ISBN (Electronic)	9789400728943
ISBN (Print)	9789400728936
DOIs	https://doi.org/10.1007/978-94-007-2894-3_5
State	Published - Jan 1 2012
Externally published	Yes

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© 2012 Springer Science+Business Media B.V.

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AU - Saydam, Okay

AU - Jimenez, Connie

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AB - Meningiomas are common human brain tumors usually of benign nature. These brain tumors derive from arachnoidal cells associated with brain meninges. The etiology of incidental meningiomas is unknown. A predisposing factor is ionizing radiation. Some genetic syndromes like neurofibromatosis type 2 are associated with meningiomas. Here we highlight the clinical needs and review recent progress made in the field of genomics and proteomics. Finally, we focus on minichromosome maintenance proteins as potential novel markers for early diagnosis of meningioma.

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BT - Tumors of the Central Nervous System, Volume 7

PB - Springer Netherlands

ER -

Meningiomas: Clinical needs and molecular insights

Abstract

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