A test of the relative merits of timed melatonin for the treatment of cardiac ischemia as well as hypertension refractory to other drugs is documented against the background of earlier chronobiological studies on blood pressure (BP), disease risks, circadian hyper-amplitude-tension and melatonin effects broadly.
Bibliographical noteFunding Information:
This study was supported by the US National Institutes of Health (GM-13981), and the University of Minnesota Supercomputing Institute.
- Conventional treatment
- Drug-refractory hypertension