Melatonin, refractory hypertension, myocardial ischemia and other challenges in nightly blood pressure lowering

Rina Mikhailovna Zaslavskaya, Galina Victorovna Lilitsa, G. S. Dilmagambetova, Franz Halberg, Germaine G Cornelissen-Guillaume, Kuniaki Otsuka, Ram B. Singh, Alexander Stoynev, Ognian Ikonomov, Roberto Tarquini, Federico Perfetto, Othild Schwartzkopff, Earl E. Bakken

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

A test of the relative merits of timed melatonin for the treatment of cardiac ischemia as well as hypertension refractory to other drugs is documented against the background of earlier chronobiological studies on blood pressure (BP), disease risks, circadian hyper-amplitude-tension and melatonin effects broadly.

Original languageEnglish (US)
Pages (from-to)S129-S134
JournalBiomedicine and Pharmacotherapy
Volume58
Issue numberSUPPL. 1
DOIs
StatePublished - Oct 2004

Bibliographical note

Funding Information:
This study was supported by the US National Institutes of Health (GM-13981), and the University of Minnesota Supercomputing Institute.

Keywords

  • Conventional treatment
  • Drug-refractory hypertension
  • MESOR-hypertension
  • Melatonin

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