TY - JOUR
T1 - Medical Management of Chronic Pancreatitis in Children
T2 - A Position Paper by the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Pancreas Committee
AU - Freeman, A. Jay
AU - Maqbool, Asim
AU - Bellin, Melena D.
AU - Goldschneider, Kenneth R.
AU - Grover, Amit S.
AU - Hartzell, Cheryl
AU - Piester, Travis L.
AU - Szabo, Flora
AU - Kiernan, Bridget Dowd
AU - Khalaf, Racha
AU - Kumar, Rakesh
AU - Rios, Mirta
AU - Husain, Sohail Z.
AU - Morinville, Veronique D.
AU - Abu-El-Haija, Maisam
N1 - Publisher Copyright:
© 2021 Lippincott Williams and Wilkins. All rights reserved.
PY - 2021/2/1
Y1 - 2021/2/1
N2 - This position paper summarizes the current understanding of the medical management of chronic pancreatitis (CP) in children in light of the existing medical literature, incorporating recent advances in understanding of nutrition, pain, lifestyle considerations, and sequelae of CP. This article complements and is intended to integrate with parallel position papers on endoscopic and surgical aspects of CP in children. Concepts and controversies related to pancreatic enzyme replacement therapy (PERT), the use of antioxidants and other CP medical therapies are also reviewed. Highlights include inclusion of tools for medical decision-making for PERT, CP-related diabetes, and multimodal pain management (including an analgesia ladder). Gaps in our understanding of CP in children and avenues for further investigations are also reviewed.
AB - This position paper summarizes the current understanding of the medical management of chronic pancreatitis (CP) in children in light of the existing medical literature, incorporating recent advances in understanding of nutrition, pain, lifestyle considerations, and sequelae of CP. This article complements and is intended to integrate with parallel position papers on endoscopic and surgical aspects of CP in children. Concepts and controversies related to pancreatic enzyme replacement therapy (PERT), the use of antioxidants and other CP medical therapies are also reviewed. Highlights include inclusion of tools for medical decision-making for PERT, CP-related diabetes, and multimodal pain management (including an analgesia ladder). Gaps in our understanding of CP in children and avenues for further investigations are also reviewed.
KW - chronic pancreatitis
KW - nutrition
KW - pain management
KW - position paper
KW - sequelae of chronic pancreatitis
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U2 - 10.1097/MPG.0000000000003001
DO - 10.1097/MPG.0000000000003001
M3 - Article
C2 - 33230082
AN - SCOPUS:85099721834
SN - 0277-2116
VL - 72
SP - 324
EP - 340
JO - Journal of pediatric gastroenterology and nutrition
JF - Journal of pediatric gastroenterology and nutrition
IS - 2
ER -
