Medical dissolution of feline struvite urocystoliths

C. A. Osborne, Jody P Lulich, J. M. Kruger, David J Polzin, G. R. Johnston, R. A. Kroll

Research output: Contribution to journalArticlepeer-review

50 Scopus citations

Abstract

The efficacy of a diet designed to facilitate dissolution of feline magnesium ammonium phosphate (struvite) uroliths was evaluated in 30 cases of urocystoliths, involving 27 cats. The number of urocystoliths, per cat varied from 1 to 5. In 20 cases of urolithiasis, sterile struvite uroliths dissolved in a mean of 36 days after initiation of dietary treatment. In 5 cases of urolithiasis, struvite urocystoliths associated with urease-negative bacterial urinary tract infection dissolved in a mean of 23 days after initiation of dietary and antimicrobial treatment. In 3 cases of urolithiasis, struvite urocystoliths associated with urease-positive staphylococcal urinary tract infection dissolved in a mean of 79 days after initiation of dietary and antimicrobial treatment. Dissolution of uroliths in cats fed the treatment diet was associated with concomitant remission of dysuria, hematuria, and pyuria, and reduction in urine pH and stuvite crystalluria. In one case, a urocystolith composed of 100% ammonium urate, and in another case, a urolith composed of 60% calcium phosphate, 20% calcium oxalate, and 20% magnesium ammonium phosphate did not dissolve.

Original languageEnglish (US)
Pages (from-to)1053-1068
Number of pages16
JournalJournal of the American Veterinary Medical Association
Volume196
Issue number7
StatePublished - Jul 25 1990

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