Medical dissolution and prevention of canine struvite urolithiasis: Twenty years of experience

C. A. Osborne, J. P. Lulich, D. J. Polzin, T. A. Allen, J. M. Kruger, J. W. Bartges, L. A. Koehler, L. K. Ulrich, K. A. Bird, L. L. Swanson

Research output: Contribution to journalReview articlepeer-review

50 Scopus citations


Two types of canine struvite uroliths have been recognized: infection- induced struvite is the most common type; sterile struvite is uncommonly recognized. Infection-induced struvite is most commonly associated with urease-producing staphylococcal UTI. For dogs that qualify, medical dissolution is an effective method of treatment. Medical dissolution protocols encompass: (1) eradication or control of UTI; (2) use of calculolytic diets; and (3) administration of urease inhibitors to patients with persistent UTI caused by urease-producing microbes.

Original languageEnglish (US)
Pages (from-to)73-111
Number of pages39
JournalVeterinary Clinics of North America - Small Animal Practice
Issue number1
StatePublished - 1999

Bibliographical note

Funding Information:
We thank I. Millan for helpful discussion on statistical analysis and M. Messman for editorial assistance. This work was supported by grants from the Comision Asesora Investigacion Cien-tifico y Tecnica (CICYT), FIS 87/875, 88/1547 and Severo Ochoa-Ferrer Foundation award (to J.J.L.L.). CPH Neural Transplantation group are: A. El Barkani, J.C. Gomez Angulo and B. Brera and also J. Uria and R. Martinez).


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