Mechanistic study of the oxidative N-dealkylation reactions of bis(μ-oxo)dicopper complexes

Keyphrases

• Monooxygenase 100%
• Oxidative Dealkylation 100%
• Dicopper Complex 100%
• Mechanistic Studies 100%
• Dicopper 100%
• Cytochrome P450 (CYP450) 66%
• Ketones 66%
• Aldehydes 66%
• C-H Bond 66%
• Kinetic Isotope Effect 66%
• 18O-labeling 66%
• N-dealkylation 66%
• Dopamine 33%
• Tunneling 33%
• Behaving 33%
• Temperature Effect 33%
• Glycine 33%
• Labeling Experiment 33%
• Oxygen Atom 33%
• C-H Bond Cleavage 33%
• Electrophile 33%
• Isotopic Labeling 33%
• Rate-determining Step 33%
• Hydroxyl 33%
• Double Labeling 33%
• Activation Parameters 33%
• Diamagnetic 33%
• First-order Kinetics 33%
• Bond Scission 33%
• Benzyl 33%
• Metalloenzymes 33%
• Secondary Amines 33%
• 1,4,7-triazacyclononane 33%
• Solution Analysis 33%
• Macrocyclic Ligands 33%
• Organic Products 33%
• Concerted Mechanism 33%
• Eyring 33%
• Hammett Study 33%
• Copper Removal 33%
• Carbinolamine 33%
• Active Oxidants 33%

Chemistry

• Mechanistic Study 100%
• Dealkylation 100%
• Ketone 66%
• Monooxygenase 66%
• Cytochrome P450 66%
• Aldehyde 66%
• Isotope Effect 66%
• Deuterium 66%
• Hydroxyl 33%
• Diamagnetic 33%
• Metalloenzyme 33%
• Secondary Amine 33%
• Macrocyclic Ligand 33%
• Kinetic Order 33%
• Rate-Determining Step 33%
• Peptidylglycine 33%
• Electrophile 33%
• Monooxygenase Reaction 33%
• Oxygen Atom 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Hydrogen Bond 100%
• Cytochrome P450 66%
• Unspecific Monooxygenase 66%
• Oxygen 18 66%
• Aldehyde 66%
• Deuterium 66%
• Bond Cleavage 33%
• Dopamine Beta Monooxygenase 33%
• Electrophile 33%
• Oxidizing Agent 33%