Mechanistic studies on the reduction of TCE by cobalamin

Angela D. Follett, Kristopher McNeill

Research output: Contribution to journalConference articlepeer-review

Abstract

Trichloroethylene (TCE) is an environmental contaminant that is subject to reductive degradation in natural and engineered systems. The reaction pathway for cobalamin, a common catalyst for reductive dechlorination, is unknown and both an outer sphere and a non-outer-sphere mechanism have been proposed. To further explore the role of the intermediates in the catalytic cycle, the reduction of cis-1,2- dichlorovinyl(pyridine)cobaloxime (1) , a model complex for the proposed intermediate formed in the dechlorination of TCE by cobalamin, was studied. The reduction of 1 was performed by again applying well-characterized outer-sphere electron-transfer agents and cobalamin in the presence of H atom and proton donor species to identify the presence of chlorovinyl radicals and anions. This work provides a further understanding of the cobalamin reduction of TCE. This is an abstract of a paper presented at the 231st ACS National Meeting (Atlanta, GA 3/26-30/2006).

Original languageEnglish (US)
Pages (from-to)878-879
Number of pages2
JournalACS, Division of Environmental Chemistry - Preprints of Extended Abstracts
Volume46
Issue number1
StatePublished - May 22 2006
Event231st ACS National Meeting, 2006 - Atlanta, GA, United States
Duration: Mar 26 2006Mar 30 2006

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