Mechanisms of selective motor neuron death in transgenic mouse models of motor neuron disease

Keyphrases

• Transgenic Mouse Model 100%
• Motor Neuron Disease 100%
• Superoxide Dismutase 1 (SOD1) 100%
• Familial ALS 100%
• Cytoplasmic Enzyme 66%
• Neurofilament 66%
• Disease Progression 33%
• Therapeutic Strategies 33%
• Pathologic 33%
• Neuronal Death 33%
• Hypothesis Testing 33%
• Skeletal muscle Atrophy 33%
• Specific Mechanisms 33%
• Progressive Weakness 33%
• Point mutant 33%
• Familial Disease 33%
• Axonal Degeneration 33%
• Neurofilament Light (NF-L) 33%
• Axonal Swelling 33%
• Mutant Enzyme 33%

Neuroscience

• Copper Zinc Superoxide Dismutase 100%
• Motor Neuron Disease 100%
• Motor Neuron 100%
• Nerve Fiber Degeneration 66%
• Neurofilament 66%
• Neuronal Cell Death 33%
• Skeletal Muscle Atrophy 33%
• Axonal Degeneration 33%