Mechanisms and management of renal dysfunction in heart failure

Inder Anand, Sumeet S. Chugh

Research output: Contribution to journalReview articlepeer-review

26 Scopus citations

Abstract

The syndrome of congestive heart failure is characterized by activation of many neurohormonal systems with vasoconstrictor and vasodilator actions. Data suggest that the stimulus that evokes this response is a threat to the arterial blood pressure. The long-term consequences of this response on the kidney are retention of sodium and water. Strategies designed to reverse the effects of these neurohormones on the kidney have so far had limited success.

Original languageEnglish (US)
Pages (from-to)251-258
Number of pages8
JournalCurrent opinion in cardiology
Volume12
Issue number3
DOIs
StatePublished - 1997

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