Mechanism and applications of Rieske non-heme iron dioxygenases

Research output: Contribution to journalReview articlepeer-review

75 Scopus citations

Abstract

Oxygenases are a broad class of enzymes which are important for the catabolism or recycling of organic matter in the environment. Bacterial catabolism of hydrocarbons and substituted aromatic compounds often uses dioxygenases containing a Rieske iron-sulfur cluster and a non-heme iron center. The dioxygenases have been useful in producing oxygenated materials directly, or indirectly by generating chiral synthetic intermediates. The recent availability of protein structures and gene sequences provides new opportunities for expanding the usefulness of this enzyme class.

Original languageEnglish (US)
Pages (from-to)577-587
Number of pages11
JournalEnzyme and Microbial Technology
Volume31
Issue number5
DOIs
StatePublished - Oct 3 2002

Keywords

  • Bacteria
  • Chiral synthon
  • Cis-diol
  • Dioxygenase
  • Mechanism
  • Rieske

Fingerprint Dive into the research topics of 'Mechanism and applications of Rieske non-heme iron dioxygenases'. Together they form a unique fingerprint.

Cite this