Mature middle and inner ears express Chd7 and exhibit distinctive pathologies in a mouse model of CHARGE syndrome

Keyphrases

• Mouse Model 100%
• Inner Ear 100%
• Middle Ear 100%
• CHD7 100%
• CHARGE Syndrome 100%
• Hair Cell Loss 22%
• Noise Exposure 22%
• Scanning Electron Microscopy 11%
• Cell Morphology 11%
• Hearing Impairment 11%
• Neurogenesis 11%
• Wild Mice 11%
• Mutant Mice 11%
• Heterozygous mutation 11%
• Vestibular Disorders 11%
• Outer Hair Cell 11%
• Hair Cell 11%
• Vestibular 11%
• Ear Structure 11%
• Morphological Characteristics 11%
• Multiple Anomalies 11%
• Conductive Hearing Loss 11%
• Immunostaining 11%
• Distortion Product Otoacoustic Emission (DPOAE) 11%
• Prestin 11%
• Sensory Epithelium 11%
• Auditory Brainstem Response Testing 11%
• Hearing Threshold 11%
• Chromodomain 11%
• Inner Hair Cell 11%
• Threshold Shift 11%
• Sudden Sensorineural Hearing Loss (SSNHL) 11%
• DNA-binding Proteins 11%
• Spiral Ganglion Neurons 11%
• Dysgenesis 11%
• Broadband Noise 11%
• Semicircular Canal 11%
• Cochlear Innervation 11%
• Middle Ear Ossicles 11%

Neuroscience

• Cell Loss 100%
• Auditory Brainstem Response 50%
• DNA-binding Protein 50%
• Sensorineural Hearing Loss 50%
• Conductive Hearing Loss 50%
• Sensation of Hearing 50%
• Scanning Electron Microscopy 50%
• Cochlea 50%
• Semicircular Canal 50%
• Prestin 50%
• Innervation 50%
• Immunohistochemistry 50%
• Neurogenesis 50%
• Spiral Ganglion Neuron 50%