Mathematical model of vascular and intracellular freezing in biological tissue

John C. Bischof, Boris Rubinsky

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

A set of heat and mass transfer equations is developed to predict vascular as well as intracellular ice formation during freezing in biological tissue. A modified Krogh unit with vascular and cellular compartments is used. In the model, intracellular ice formation is predicted by a probability integral with functional dependence on cell-compartment volume, temperature, and time. Finite-difference computer simulations qualitatively predict the amount and location of vascular and intracellular ice, the temperature distribution in the tissue, and the position of the partial and total freezing interfaces at any time.

Original languageEnglish (US)
Title of host publicationAdvaces in Biological Heat and Mass Transfer - 1992
PublisherPubl by ASME
Pages17-25
Number of pages9
ISBN (Print)0791811115
StatePublished - Dec 1 1992
EventWinter Annual Meeting of the American Society of Mechanical Engineers - Anaheim, CA, USA
Duration: Nov 8 1992Nov 13 1992

Publication series

NameAmerican Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD
Volume231
ISSN (Print)0272-5673

Other

OtherWinter Annual Meeting of the American Society of Mechanical Engineers
CityAnaheim, CA, USA
Period11/8/9211/13/92

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