Abstract
Background: Prenatal supplementation has been inversely associated with childhood, but not with infant, leukaemia. Methods: Mothers of 443 cases of infant leukaemia diagnosed during 1996-2006 and 324 frequency-matched controls completed interviews. Associations were evaluated by unconditional logistic regression. Results : We observed no associations between prenatal vitamin (odds ratio (OR)0.79, 95% confidence interval (CI): 0.44-1.42) or iron supplementation (OR1.07, 95% CI: 0.75-1.52) and infant leukaemia after adjustment for race/ethnicity and income. Similar results were observed for leukaemia subtypes analysed separately.ConclusionThe observed null associations may be attributable to high supplementation rates and/or national fortification programmes.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1724-1728 |
| Number of pages | 5 |
| Journal | British Journal of Cancer |
| Volume | 103 |
| Issue number | 11 |
| DOIs | |
| State | Published - Nov 23 2010 |
Bibliographical note
Funding Information:This research was supported by the National Institutes of Health Grants R01 CA79940, T32 CA99936, U10 CA13539, and U10 CA98543; Grant P30 CA77588 (University of Minnesota Masonic Cancer Center shared resource: Health Survey Research Center); and the Children’s Cancer Research Fund, Minneapolis, MN, USA.
Keywords
- epidemiology
- infants
- leukaemia
- vitamin
