Maternal-fetal transmission of the Lyme disease spirochete, Borrelia burgdorferi

P. A. Schlesinger, P. H. Duray, B. A. Burke, A. C. Steere, M. T. Stillman

Research output: Contribution to journalArticle

147 Citations (Scopus)

Abstract

Lyme disease usually begins with a characteristic skin lesion, erythema chronicum migrans, accompanied by 'influenza-like' or 'meningitis-like' symptoms. Some patients later develop cardiac abnormalities such as atrioventricular heart block or myopericarditis, neurologic complications, or intermittent attacks of arthritis. The causative agent, the Lyme disease spirochete Borrelia burgdorferi, is transmitted by Ixodes dammini or related ixodid ticks. Antibiotic treatment with tetracycline or penicillin is usually curative. We report the case of a woman who developed Lyme disease during the first trimester of pregnancy. She did not receive antibiotic therapy. Her infant, born at 35 weeks gestational age, died of congenital heart disease during the first week of life. Histologic examination of autopsy material showed the Lyme disease spirochete in the spleen, kidneys, and bone marrow.

Original languageEnglish (US)
Pages (from-to)67-68
Number of pages2
JournalAnnals of internal medicine
Volume103
Issue number1
DOIs
StatePublished - Jan 1 1985

Fingerprint

Borrelia burgdorferi
Lyme Disease
Mothers
Erythema Chronicum Migrans
Anti-Bacterial Agents
Ixodes
Heart Block
Atrioventricular Block
Ticks
First Pregnancy Trimester
Tetracycline
Meningitis
Penicillins
Human Influenza
Nervous System
Gestational Age
Arthritis
Autopsy
Heart Diseases
Spleen

Cite this

Schlesinger, P. A., Duray, P. H., Burke, B. A., Steere, A. C., & Stillman, M. T. (1985). Maternal-fetal transmission of the Lyme disease spirochete, Borrelia burgdorferi. Annals of internal medicine, 103(1), 67-68. https://doi.org/10.7326/0003-4819-103-1-67

Maternal-fetal transmission of the Lyme disease spirochete, Borrelia burgdorferi. / Schlesinger, P. A.; Duray, P. H.; Burke, B. A.; Steere, A. C.; Stillman, M. T.

In: Annals of internal medicine, Vol. 103, No. 1, 01.01.1985, p. 67-68.

Research output: Contribution to journalArticle

Schlesinger, PA, Duray, PH, Burke, BA, Steere, AC & Stillman, MT 1985, 'Maternal-fetal transmission of the Lyme disease spirochete, Borrelia burgdorferi', Annals of internal medicine, vol. 103, no. 1, pp. 67-68. https://doi.org/10.7326/0003-4819-103-1-67
Schlesinger, P. A. ; Duray, P. H. ; Burke, B. A. ; Steere, A. C. ; Stillman, M. T. / Maternal-fetal transmission of the Lyme disease spirochete, Borrelia burgdorferi. In: Annals of internal medicine. 1985 ; Vol. 103, No. 1. pp. 67-68.
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