Materials surface effects on biological interactions

Josep A. Planell, Melba Navarro, George Altankov, Conrado Aparicio, Elisabeth Engel, Javier Gil, Maria Pau Ginebra, Damien Lacroix

Research output: Chapter in Book/Report/Conference proceedingChapter

20 Scopus citations


At present it is well accepted that different surface properties play a strong role in the interaction between synthetic materials and biological entities. Surface properties such as surface energy, topography, surface chemistry and crystallinity affect the protein adsorption mechanisms as well as cell behaviour in terms of attachment, proliferation and differentiation. The aim of this chapter is to show the most relevant processes and interactions that take place during the first stages of contact between the material and the physiological environment. Some examples show that the modification of different biomaterials surfaces affects both protein adsorption and cell behaviour.

Original languageEnglish (US)
Title of host publicationAdvances in Regenerative Medicine
Subtitle of host publicationRole of Nanotechnology, and Engineering Principles
PublisherSpringer Verlag
Number of pages20
ISBN (Print)9789048187881
StatePublished - 2010

Publication series

NameNATO Science for Peace and Security Series A: Chemistry and Biology
ISSN (Print)1874-6489


  • Cell-material interactions
  • Surface chemistry
  • Surface properties
  • Topography


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