Mass Spectrometric Quantitation of N′-Nitrosonornicotine-1 N-oxide in the Urine of Cigarette Smokers and Smokeless Tobacco Users

Keyphrases

• 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone 11%
• Ammonium Sulfamate 5%
• Cancer Etiology 5%
• Cigarette Smokers 100%
• Detoxification Pathways 5%
• First Detection 5%
• Glucuronide 5%
• Human Groups 5%
• Human Urine 5%
• Hydroxylation 5%
• International Agency for Research on Cancer 5%
• Mass Spectrometry 100%
• Mean Concentration 5%
• Metabolic Activation 5%
• Metabolic Fate 5%
• N'-nitrosonornicotine 100%
• N-oxidation 5%
• N-oxides 100%
• Nitrosation 5%
• Nitrosation Reaction 5%
• Non-smokers 5%
• Nornicotine 5%
• Oxidation Mechanism 5%
• Oxides 5%
• Pyridine N 5%
• Sample Preparation 5%
• Smokeless Tobacco Users 100%
• Tobacco Products 5%
• Tobacco Users 5%
• Urine Samples 5%

Pharmacology, Toxicology and Pharmaceutical Science

• 4 (Methylnitrosamino) 1 (3 Pyridyl) 1 Butanol 5%
• 4 (Methylnitrosamino) 1 (3 Pyridyl) 1 Butanone 5%
• Biological Marker 16%
• Detoxication 5%
• Glucuronide 5%
• Malignant Neoplasm 11%
• N-Nitrosonornicotine 100%
• NNK 11%
• Nornicotine 5%
• Sulfamate 5%