Marked hypodiploidy in blast phase chronic myelogenous leukemia: Report of a case and review of the literature

Michael L. Cibull; Mark E. Thompson; Linda Smith; C. Darrell Jennings; Michael A. Doukas; Edward J. Pavlik; Deborah E. Powell

doi:10.1002/ajh.2830240309

Marked hypodiploidy in blast phase chronic myelogenous leukemia: Report of a case and review of the literature

Michael L. Cibull, Mark E. Thompson, Linda Smith, C. Darrell Jennings, Michael A. Doukas, Edward J. Pavlik, Deborah E. Powell

Laboratory Medicine and Pathology

Research output: Contribution to journal › Article › peer-review

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Abstract

The emergence of a near‐haploid clone of cells in blast phase chronic myelogenous leukemia is an unusual event. We report such a case and review eight other cases described in the English literature. The significance of the substantial loss of genetic material is discussed as is the phenotypic and genotypic heterogeneity observed in this group of patients.

Original language	English (US)
Pages (from-to)	293-299
Number of pages	7
Journal	American Journal of Hematology
Volume	24
Issue number	3
DOIs	https://doi.org/10.1002/ajh.2830240309
State	Published - Mar 1987

Keywords

blast phase chronic myelogenous leukemia
cytogenetics
hypodiploidy

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10.1002/ajh.2830240309

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abstract = "The emergence of a near‐haploid clone of cells in blast phase chronic myelogenous leukemia is an unusual event. We report such a case and review eight other cases described in the English literature. The significance of the substantial loss of genetic material is discussed as is the phenotypic and genotypic heterogeneity observed in this group of patients.",

keywords = "blast phase chronic myelogenous leukemia, cytogenetics, hypodiploidy",

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year = "1987",

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AU - Pavlik, Edward J.

AU - Powell, Deborah E.

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Marked hypodiploidy in blast phase chronic myelogenous leukemia: Report of a case and review of the literature

Abstract

Keywords

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