Marked hypodiploidy in blast phase chronic myelogenous leukemia: Report of a case and review of the literature

Michael L. Cibull; Mark E. Thompson; Linda Smith; C. Darrell Jennings; Michael A. Doukas; Edward J. Pavlik; Deborah E. Powell

doi:10.1002/ajh.2830240309

Marked hypodiploidy in blast phase chronic myelogenous leukemia: Report of a case and review of the literature

Michael L. Cibull, Mark E. Thompson, Linda Smith, C. Darrell Jennings, Michael A. Doukas, Edward J. Pavlik, Deborah E. Powell

Laboratory Medicine and Pathology

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

The emergence of a near‐haploid clone of cells in blast phase chronic myelogenous leukemia is an unusual event. We report such a case and review eight other cases described in the English literature. The significance of the substantial loss of genetic material is discussed as is the phenotypic and genotypic heterogeneity observed in this group of patients.

Original language	English (US)
Pages (from-to)	293-299
Number of pages	7
Journal	American Journal of Hematology
Volume	24
Issue number	3
DOIs	https://doi.org/10.1002/ajh.2830240309
State	Published - Mar 1987

Keywords

blast phase chronic myelogenous leukemia
cytogenetics
hypodiploidy

Access

10.1002/ajh.2830240309

Fingerprint Dive into the research topics of 'Marked hypodiploidy in blast phase chronic myelogenous leukemia: Report of a case and review of the literature'. Together they form a unique fingerprint.

Cite this

Marked hypodiploidy in blast phase chronic myelogenous leukemia : Report of a case and review of the literature. / Cibull, Michael L.; Thompson, Mark E.; Smith, Linda; Jennings, C. Darrell; Doukas, Michael A.; Pavlik, Edward J.; Powell, Deborah E.

In: American Journal of Hematology, Vol. 24, No. 3, 03.1987, p. 293-299.

Research output: Contribution to journal › Article › peer-review

@article{cd00801e11e1459c8efc598c883675e9,

title = "Marked hypodiploidy in blast phase chronic myelogenous leukemia: Report of a case and review of the literature",

abstract = "The emergence of a near‐haploid clone of cells in blast phase chronic myelogenous leukemia is an unusual event. We report such a case and review eight other cases described in the English literature. The significance of the substantial loss of genetic material is discussed as is the phenotypic and genotypic heterogeneity observed in this group of patients.",

keywords = "blast phase chronic myelogenous leukemia, cytogenetics, hypodiploidy",

author = "Cibull, {Michael L.} and Thompson, {Mark E.} and Linda Smith and Jennings, {C. Darrell} and Doukas, {Michael A.} and Pavlik, {Edward J.} and Powell, {Deborah E.}",

year = "1987",

month = mar,

doi = "10.1002/ajh.2830240309",

language = "English (US)",

volume = "24",

pages = "293--299",

journal = "American Journal of Hematology",

issn = "0361-8609",

publisher = "Wiley-Liss Inc.",

number = "3",

}

TY - JOUR

T1 - Marked hypodiploidy in blast phase chronic myelogenous leukemia

T2 - Report of a case and review of the literature

AU - Cibull, Michael L.

AU - Thompson, Mark E.

AU - Smith, Linda

AU - Jennings, C. Darrell

AU - Doukas, Michael A.

AU - Pavlik, Edward J.

AU - Powell, Deborah E.

PY - 1987/3

Y1 - 1987/3

N2 - The emergence of a near‐haploid clone of cells in blast phase chronic myelogenous leukemia is an unusual event. We report such a case and review eight other cases described in the English literature. The significance of the substantial loss of genetic material is discussed as is the phenotypic and genotypic heterogeneity observed in this group of patients.

AB - The emergence of a near‐haploid clone of cells in blast phase chronic myelogenous leukemia is an unusual event. We report such a case and review eight other cases described in the English literature. The significance of the substantial loss of genetic material is discussed as is the phenotypic and genotypic heterogeneity observed in this group of patients.

KW - blast phase chronic myelogenous leukemia

KW - cytogenetics

KW - hypodiploidy

UR - http://www.scopus.com/inward/record.url?scp=0023138393&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023138393&partnerID=8YFLogxK

U2 - 10.1002/ajh.2830240309

DO - 10.1002/ajh.2830240309

M3 - Article

C2 - 3469912

AN - SCOPUS:0023138393

VL - 24

SP - 293

EP - 299

JO - American Journal of Hematology

JF - American Journal of Hematology

SN - 0361-8609

IS - 3

ER -