Mapping of the gene encoding the β-subunit of H+,K+-ATPase to human chromosome 13q34 by fluorescence in situ hybridization

Il Song; David R. Brown; Tadataka Yamada; Jeffrey M. Trent

doi:10.1016/S0888-7543(05)80142-9

Mapping of the gene encoding the β-subunit of H⁺,K⁺-ATPase to human chromosome 13q34 by fluorescence in situ hybridization

Il Song, David R. Brown, Tadataka Yamada, Jeffrey M. Trent

Chronic Disease Biology

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Original language	English (US)
Pages (from-to)	1114-1115
Number of pages	2
Journal	Genomics
Volume	14
Issue number	4
DOIs	https://doi.org/10.1016/S0888-7543(05)80142-9
State	Published - Dec 1992

Bibliographical note

Funding Information:
The genes encoding the a-and /3-subunits of gastric H+,K+-ATPase from several mammalian species have been cloned and sequenced. In contrast to the 22-exon gene encoding the a-subunit (7, 10), the/3-subunit is encoded on a gene comprising 7 exons (1, 7, 11). The human H+,K+-ATPase /3-subunit is encoded on a 1.4-kb-long cDNA (5). Its deduced amino acid sequence bears >80% identity to that of rabbits, rodents, cattle, and swine (13, 14, 16). Using fluorescence in situ hybridization (FISH), we have recently mapped the gene 1 This work was supported in part by NIH Grants R01-DK34306, R01-DK33500, and P30-CA-46592 and funds from the University of Michigan Gastrointestinal Peptide Research Center (NIH Grant P30-DK34933). D.R.B. is a Visiting Research Investigator supported in part by National Research Service Award F33-DK08686.

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@article{303d17b060784c5abacd844f49fe6af3,

title = "Mapping of the gene encoding the β-subunit of H+,K+-ATPase to human chromosome 13q34 by fluorescence in situ hybridization",

author = "Il Song and Brown, {David R.} and Tadataka Yamada and Trent, {Jeffrey M.}",

note = "Funding Information: The genes encoding the a-and /3-subunits of gastric H+,K+-ATPase from several mammalian species have been cloned and sequenced. In contrast to the 22-exon gene encoding the a-subunit (7, 10), the/3-subunit is encoded on a gene comprising 7 exons (1, 7, 11). The human H+,K+-ATPase /3-subunit is encoded on a 1.4-kb-long cDNA (5). Its deduced amino acid sequence bears >80% identity to that of rabbits, rodents, cattle, and swine (13, 14, 16). Using fluorescence in situ hybridization (FISH), we have recently mapped the gene 1 This work was supported in part by NIH Grants R01-DK34306, R01-DK33500, and P30-CA-46592 and funds from the University of Michigan Gastrointestinal Peptide Research Center (NIH Grant P30-DK34933). D.R.B. is a Visiting Research Investigator supported in part by National Research Service Award F33-DK08686.",

year = "1992",

month = dec,

doi = "10.1016/S0888-7543(05)80142-9",

language = "English (US)",

volume = "14",

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journal = "Genomics",

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T1 - Mapping of the gene encoding the β-subunit of H+,K+-ATPase to human chromosome 13q34 by fluorescence in situ hybridization

AU - Song, Il

AU - Brown, David R.

AU - Yamada, Tadataka

AU - Trent, Jeffrey M.

N1 - Funding Information: The genes encoding the a-and /3-subunits of gastric H+,K+-ATPase from several mammalian species have been cloned and sequenced. In contrast to the 22-exon gene encoding the a-subunit (7, 10), the/3-subunit is encoded on a gene comprising 7 exons (1, 7, 11). The human H+,K+-ATPase /3-subunit is encoded on a 1.4-kb-long cDNA (5). Its deduced amino acid sequence bears >80% identity to that of rabbits, rodents, cattle, and swine (13, 14, 16). Using fluorescence in situ hybridization (FISH), we have recently mapped the gene 1 This work was supported in part by NIH Grants R01-DK34306, R01-DK33500, and P30-CA-46592 and funds from the University of Michigan Gastrointestinal Peptide Research Center (NIH Grant P30-DK34933). D.R.B. is a Visiting Research Investigator supported in part by National Research Service Award F33-DK08686.

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