Map-Fingerprint-Dot Changes in the Corneal Epithelial Basement Membrane Following Radial Keratotomy

J. Daniel Nelson, Patricia Williams, Richard L. Lindstrom, Donald J. Doughman

Research output: Contribution to journalArticlepeer-review

35 Scopus citations


Corneal epithelial opacities similar to those seen in corneal epithelial basement membrane dystrophy were seen in 33 of 71 eyes following radial keratotomy. These changes were clinically indistinguishable from those seen in map-fingerprint-dot dystrophy with map type changes seen most often. Basement membrane changes tended to be transient (persisting less than 3 months in 75.3% of eyes) and not usually visually significant. However, three eyes had changes which persisted for 12 months. Most eyes with basement membrane changes had involvement of less than one-half quadrant of the corneal (68%). Involvement of two or more quadrants occurred in 9.4% of eyes with these changes. One eye had visually significant changes which persisted for 3 months. There were no episodes of recurrent erosion.

Original languageEnglish (US)
Pages (from-to)199-205
Number of pages7
Issue number2
StatePublished - 1985

Bibliographical note

Funding Information:
Supported in part by National Institutes of Health Grant R01·E40376704.


  • basement membrane changes
  • corneal epithelial basement membrane dystrophy
  • map-fingerprint-dot dystrophy
  • radial keratotomy
  • refractive surgery


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