Management of psychiatric features in frontotemporal dementia

Jamie Starks, Michael Rosenbloom

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Frontotemporal dementia (FTD) refers to a group of neurodegenerative disorders that affects the frontotemporal cortices, resulting in progressive decline affecting cognitive and behavioral function. FTD is most commonly divided into three clinical syndromes: behavioral variant frontotemporal dementia (bvFTD) and two language variants, semantic variant primary progressive aphasia and nonfluent/ agrammatic variant primary progressive aphasia. bvFTD may present with symptoms that overlap with psychiatric disorders. Treatment in FTD is symptomatic rather than disease-modifying, consisting of both nonpharmacological behavioral interventions as well as pharmacological treatments such as selective serotonin reuptake inhibitors and neuroleptics. This review discusses a diagnostic approach to FTD followed by a review of the literature on both pharmacological and nonpharmacological interventions for the commonly observed psychiatric symptoms in this patient population.

Original languageEnglish (US)
Pages (from-to)246-257
Number of pages12
JournalPsychiatric annals
Issue number5
StatePublished - May 2017

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