Abstract
Hypertension is common in patients with chronic kidney disease (CKD) and contributes to risk of progression of CKD and cardiovascular disease. Many factors including alterations in salt and water balance, the sympathetic nervous system, and the renin-angiotensin-aldosterone system underlie the pathophysiology of hypertension in this setting. Careful measurement of blood pressure, including out-of-office measurement, is important. Goal blood pressure for patients with CKD is less than 130/80mmHg. Restriction of dietary salt intake is an important nonpharmacologic intervention, and inhibitors of the renin-angiotensin axis are the cornerstone of drug therapy, especially in patients with proteinuria.
| Original language | English (US) |
|---|---|
| Title of host publication | Chronic Renal Disease |
| Publisher | Elsevier |
| Pages | 1001-1011 |
| Number of pages | 11 |
| ISBN (Electronic) | 9780128158760 |
| ISBN (Print) | 9780128158777 |
| DOIs | |
| State | Published - Jan 1 2019 |
Bibliographical note
Publisher Copyright:© 2020 Elsevier Inc. All rights reserved.
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Chronic kidney disease
- Hypertension
- Proteinuria
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