Management of Hypertension in Chronic Kidney Disease

Mahboob Rahman, Paul Drawz, George Thomas, Jeffrey Turner

Research output: Chapter in Book/Report/Conference proceedingChapter


Hypertension is common in patients with chronic kidney disease (CKD) and contributes to risk of progression of CKD and cardiovascular disease. Many factors including alterations in salt and water balance, the sympathetic nervous system, and the renin-angiotensin-aldosterone system underlie the pathophysiology of hypertension in this setting. Careful measurement of blood pressure, including out-of-office measurement, is important. Goal blood pressure for patients with CKD is less than 130/80mmHg. Restriction of dietary salt intake is an important nonpharmacologic intervention, and inhibitors of the renin-angiotensin axis are the cornerstone of drug therapy, especially in patients with proteinuria.

Original languageEnglish (US)
Title of host publicationChronic Renal Disease
Number of pages11
ISBN (Electronic)9780128158760
ISBN (Print)9780128158777
StatePublished - Jan 1 2019

Bibliographical note

Publisher Copyright:
© 2020 Elsevier Inc. All rights reserved.


  • Chronic kidney disease
  • Hypertension
  • Proteinuria


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