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Management of Acute and Late Endocrine Effects Following Childhood Cancer Treatment

  • Megan Oberle
  • , Jill L. Brodsky
  • , Adda Grimberg

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Advancements in the treatment of pediatric cancer have led to increased survival rates. The majority of adult survivors of pediatric cancers will develop a chronic disease, including endocrine disorders. The type and prevalence of the acute and late endocrine effects of cancer treatment vary widely by cancer type, treatment, and patient characteristics (age, gender, comorbidities). This chapter will describe the endocrine effects of treatment for childhood cancer both during and after treatment by endocrine system. In addition, we will review the current literature on pathophysiology, diagnosis, and treatment of the endocrine effects commonly seen in survivors of pediatric cancers.

Original languageEnglish (US)
Title of host publicationPediatric Endocrinology
Subtitle of host publicationA Practical Clinical Guide
PublisherSpringer Science+Business Media
Pages231-258
Number of pages28
ISBN (Electronic)9783319737829
ISBN (Print)9783319737812
DOIs
StatePublished - Jan 1 2018

Bibliographical note

Publisher Copyright:
© Springer International Publishing AG, part of Springer Nature 2018

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Acute effects
  • Adrenal insufficiency
  • Bone health
  • Cancer survivors
  • Chemotherapy
  • Cranial radiation
  • Delayed puberty
  • Diabetes insipidus
  • Fertility preservation
  • Growth failure
  • Late effects
  • Obesity
  • Pediatric cancer
  • Precocious puberty
  • Thyroid dysfunction

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