Male-specific deficits in natural reward learning in a mouse model of neurodevelopmental disorders

Keyphrases

• Striatum 100%
• Neurodevelopmental Disorders 100%
• Reward Learning 100%
• Extracellular Signal-regulated Kinase 100%
• Specific Deficits 100%
• Natural Reward 100%
• Male-specific 100%
• Mouse Models of Neurodevelopmental Disorders 100%
• Sex Differences 40%
• 16p11.2 40%
• MRNA Level 40%
• Pathophysiology 20%
• Overexpressing 20%
• Autism Spectrum Disorder 20%
• Genetic Lesions 20%
• Mouse Model 20%
• Striatal 20%
• Phosphatase 20%
• Autism 20%
• Phosphorylation 20%
• Resilience 20%
• Neuron Signaling 20%
• Striatal Plasticity 20%
• Attention Deficit Hyperactivity Disorder 20%
• Protein Level 20%
• Genetic mutation 20%
• Intracellular Signaling 20%
• Adenosine Receptors 20%
• 2 Receptor 20%
• Genetic Risk 20%
• ERK2 20%
• Protein Tyrosine Phosphatase 1B (PTP1B) 20%
• Dopamine D2 Receptor (DRD2) 20%
• Behavioral Inhibition 20%
• Indirect Pathway 20%
• Male Bias 20%
• Medium Spiny Neurons 20%
• Work Motivation 20%
• Striatal Dysfunction 20%
• Specific Vulnerability 20%
• 16p11.2 Deletion 20%
• Female-specific 20%
• Elevated Protein 20%
• Directed Learning 20%

Neuroscience

• Kinase 100%
• Striatum 71%
• Messenger RNA 42%
• Attention Deficit Hyperactivity Disorder 14%
• Adenosine Receptor 14%
• Intracellular Signaling 14%
• Protein Tyrosine Phosphatase 14%
• Pervasive Developmental Disorder 14%
• Mitogen Activated Protein Kinase 1 14%
• Gene Mutation 14%
• Dopamine Receptor D2 14%
• Medium Spiny Neuron 14%
• Phosphatase 14%