TY - JOUR
T1 - MALDI-MS data analysis for disease biomarker discovery.
AU - Yu, Weichuan
AU - Wu, Baolin
AU - Liu, Junfeng
AU - Li, Xiaoye
AU - Stone, Kathy
AU - Williams, Kenneth R.
AU - Zhao, Hongyu
N1 - Copyright:
This record is sourced from MEDLINE/PubMed, a database of the U.S. National Library of Medicine
PY - 2006
Y1 - 2006
N2 - In this chapter, we address the issue of matrix-assisted laser desorption/ionization mass spectrometry (MS) data analysis for disease biomarker discovery. We first give a general framework of MS data analysis, then focus on several key steps. After that, we show some application examples using an ovarian sera cancer dataset. Finally, we discuss the limitations of current approaches and possible future research directions.
AB - In this chapter, we address the issue of matrix-assisted laser desorption/ionization mass spectrometry (MS) data analysis for disease biomarker discovery. We first give a general framework of MS data analysis, then focus on several key steps. After that, we show some application examples using an ovarian sera cancer dataset. Finally, we discuss the limitations of current approaches and possible future research directions.
UR - http://www.scopus.com/inward/record.url?scp=33746569477&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33746569477&partnerID=8YFLogxK
U2 - 10.1385/1-59745-026-x:199
DO - 10.1385/1-59745-026-x:199
M3 - Article
C2 - 16785651
AN - SCOPUS:33746569477
SN - 1064-3745
VL - 328
SP - 199
EP - 216
JO - Methods in molecular biology (Clifton, N.J.)
JF - Methods in molecular biology (Clifton, N.J.)
ER -
